Product ID:ACRYLAMIDE ELECTROPHORESIS REAGENT, A3553
MSDS Date:04/17/1994
FSC:6810
NIIN:00N061206
MSDS Number: BXXWB

SIGMA CHEMICAL CO

ST LOUIS, MO 63178
US

Emergency Phone: 314-771-5765

Info Phone: 800-325-3010

Cage: 21076

SIGMA CHEMICAL COMPANY

14508 ST LOUIS, MO 63178 US

Telephone: 314-771-5765

Cage: 21076

ACRYLAMIDE (SARA 302/313) (CERCLA)

CAS: 79-06-1

RTECS: AS3325000

OSHA PEL 0.3 MG/M3, S

ACGIH TLV: 0.03 MG/M3,A2, S

EPA Report Quantity: 5000 LBS

DOT Report Quantity: 5000 LBS

(TESTICULAR TUMORS, UTERINE TUMORS); EFTS ON

RTECS: 9999999ZZ

BEHAVIORAL); TUMORIGENIC (CARCIN & NEOPLSTIC BY

RTECS: 9999999ZZ

REPRODUCTIVE,

RTECS: 9999999ZZ

LD50 LC50 Mixture:LD50 (ORAL RAT): 124 MG/KG.
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:YES IARC:YES OSHA:NO
Health Hazards Acute and Chronic:ACUTE: HARMFUL IF SWALLOWED,
INHALED/ABSORBED THRU SKIN. CAUSES EYE & SKIN IRRIT. MAY CAUSE CNS
DISTURB. CHRONIC: MAY ALTER GENETIC MATL. OVEREXP MAY CAUSE REPRO
DISORDERS BASED ON TESTS W/LAB ANIMALS . TARGET ORGAN DATA:
PERIPHERAL NERVE &SENSATION (FLACCID PARALYSIS W/OUT ANESTH);
BEHAVIORAL ALTERED (EFTS OF OVEREXP)
Explanation of Carcinogenicity:ACRYLAMIDE: IARC MONO, SUPP, VOL 7, PG
56, 1987: GROUP 2B. NTP 7TH ANNUAL REPORT ON CARCIN, 1994:
ANTICIPATED (ING 4)
Effects of Overexposure:HLTH HAZ: SLEEP TIME, TREMOR, CONVULSIONS/EFT
ON SEIZURE THRESHOLD, CHANGE IN MOTOR ACTIVITY, MUSCLE
CONTRACTION/SPASTICITY); LUNGS, THORAX/RESP (TUMORS); GI
(NAUS/VOMIT); BLOOD (OTHER CHANGES); SKIN & APPENDAGES (TUMORS);
PATERNAL EFTS (SPERMATOGENESIS, TESTES, EPIDIDYMIS, SPERM DUCT);
EFTS ON FERTILITY (SUP DAT)
Medical Cond Aggravated by Exposure:NONE SPECIFIED BY MANUFACTURER.

First Aid:EYES/SKIN: IMMEDIATELY FLUSH WITH COPIOUS AMOUNTS OF WATER
FOR AT LEAST 15 MINUTES WHILE REMOVING CONTAMINATED CLOTHING AND
SHOES. INHALATION: REMOVE TO FRESH AIR. IF NOT BREATHING, GIVE
ARTIFICIAL RE SPIRATION. IF BREATHING IS DIFFICULT, GIVE OXYGEN.
INGESTION: WASH OUT MOUTH WITH WATER PROVIDED PERSON IS CONSCIOUS.
CALL MD IMMEDIATELY.

Extinguishing Media:CARBON DIOXIDE, DRY CHEMICAL POWDER OR APPROPRIATE
FOAM.
Fire Fighting Procedures:WEAR NIOSH/MSHA APPROVED SCBA & FULL
PROTECTIVE EQUIPMENT . USE WATER TO COOL FIRE-EXPOSED CONTAINERS.
Unusual Fire/Explosion Hazard:CONTAINER EXPLOSION MAY OCCUR UNDER FIRE
CONDITIONS. EMITS TOXIC FUMES UNDER FIRE CONDITIONS.

Spill Release Procedures:EVACUATE AREA. WEAR SCBA, RUBBER BOOTS, AND
HEAVY RUBBER GLOVES. SWEEP UP, PLACE IN A BAG AND HOLD FOR WASTE
DISPOSAL. AVOID RAISING DUST. VENTILATE AREA AND WASH SPILL SITE
AFTER MATERIAL PICKUP IS C OMPLETE.
Neutralizing Agent:NONE SPECIFIED BY MANUFACTURER.

Handling and Storage Precautions:DO NOT BREATHE DUST. DO NOT GET IN
EYES, ON SKIN, ON CLOTHING. AVOID PROLONGED OR REPEATED EXPOSURE.
READILY ABSORBED THROUGH SKIN.
Other Precautions:KEEP TIGHTLY CLOSED. STORE IN A COOL DRY PLACE.

Respiratory Protection:WEAR APPROPRIATE NIOSH/MSHA APPROVED RESPIRATOR.
Ventilation:USE ONLY IN A CHEMICAL FUME HOOD.
Protective Gloves:CHEMICAL-RESISTANT GLOVES.
Eye Protection:ANSI APPRVD CHEM WORKERS GOGGS .
Other Protective Equipment:EMERGENCY EYEWASH & DELUGE SHOWER MEETING
ANSI DESIGN CRITERIA . WEAR PROTECTIVE CLOTHING.
Work Hygienic Practices:WASH THOROUGHLY AFTER HANDLING.
Supplemental Safety and Health
MATL TO AVOID: RADICAL INITIATORS, AIR SENSITIVE. STORE AWAY FROM HEAT
& DIRECT SUNLIGHT. EFTS OF OVEREXP: (MALE FERTILITY INDEX,
PRE-IMPLANTATION MORTALITY, POST-IMPLANTATION MORTALITY); EFTS ON
EMBR YO/FETUS (FETOTOXICITY, FETAL DEATH); SPECIFIC DEVELOPMENTAL
ABNORM (MUSCULOSKELETAL SYS); TUMORIGENIC EFTS (ING 2)

Boiling Pt:B.P. Text:257F,125C
Melt/Freeze Pt:M.P/F.P Text:>183F,>84C
Vapor Pres:1.6 @84.5C
Vapor Density:2.45
Appearance and Odor:WHITE CRYSTALLINE CHUNKS

Stability Indicator/Materials to Avoid:NO
AVOID CONT W/ACID, BASES, OXIDIZING AGENTS, REDUCING AGENTS, IRON &
IRON SALTS, COPPER, ALUMINUM, BRASS, FREE (SUP DAT)
Stability Condition to Avoid:DO NOT HEAT OVER 50C.
Hazardous Decomposition Products:TOXIC FUMES OF: CARBON MONOXIDE,
CARBON DIOXIDE, NITROGEN OXIDES, AMMONIA.
Conditions to Avoid Polymerization:DO NOT HEAT OVER 50C. MAY POLYMERIZE
ON EXPOSURE TO LIGHT.

Waste Disposal Methods:DISSOLVE/MIX MATL W/COMBUSTIBLE SOLVENT AND BURN
IN A CHEMICAL INCINERATOR EQUIPPED W/AFTERBURNER AND SCRUBBER.
OBSERVE ALL FEDERAL, STATE, AND LOCAL ENVIRONMENTAL REGULATIONS.

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